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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4A
All Species:
30.91
Human Site:
S523
Identified Species:
45.33
UniProt:
O95239
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95239
NP_036442.3
1232
139881
S523
A
L
R
Q
A
Q
M
S
K
E
L
V
E
L
N
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
S523
A
L
H
Q
A
Q
M
S
K
K
V
V
E
L
N
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
S523
A
L
R
Q
A
Q
M
S
K
E
L
V
E
L
N
Dog
Lupus familis
XP_549061
1234
139874
S524
A
L
R
Q
A
Q
M
S
K
E
L
V
E
L
N
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
S524
A
L
R
Q
A
Q
M
S
K
E
L
I
E
L
N
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
S549
Q
L
L
V
D
Q
L
S
E
E
L
A
K
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
S529
A
L
R
Q
A
Q
M
S
K
E
L
V
E
L
N
Frog
Xenopus laevis
Q91784
1226
138905
S526
A
L
R
Q
A
Q
L
S
K
E
L
I
E
L
N
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
K627
T
H
C
E
S
S
R
K
L
N
R
D
E
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
G205
M
I
K
V
M
Q
V
G
N
K
N
R
T
V
G
Honey Bee
Apis mellifera
XP_395595
1064
123475
N484
N
A
N
T
F
T
I
N
R
E
E
N
I
E
H
Nematode Worm
Caenorhab. elegans
P46873
699
78760
A120
A
F
D
H
I
F
T
A
T
A
T
T
E
N
V
Sea Urchin
Strong. purpuratus
P46872
699
78679
I120
Q
P
E
L
R
G
I
I
P
N
S
F
A
H
I
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
T454
H
D
Y
R
S
R
C
T
A
V
E
Q
R
E
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199593
1035
116715
I452
S
E
K
D
F
K
D
I
R
A
D
D
I
V
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
L349
P
A
E
L
K
Q
M
L
A
K
A
K
T
Q
I
Conservation
Percent
Protein Identity:
100
93.1
96.4
94.8
N.A.
87
27
N.A.
N.A.
74.5
68.5
25.8
N.A.
26.9
36.8
27.1
27.3
Protein Similarity:
100
95.6
97.2
97
N.A.
92.7
47.6
N.A.
N.A.
85.9
82.1
45.1
N.A.
41.4
56.3
38.4
39.3
P-Site Identity:
100
80
100
100
N.A.
93.3
33.3
N.A.
N.A.
100
86.6
6.6
N.A.
6.6
6.6
13.3
0
P-Site Similarity:
100
93.3
100
100
N.A.
100
60
N.A.
N.A.
100
100
20
N.A.
40
33.3
20
6.6
Percent
Protein Identity:
33.2
N.A.
N.A.
32.7
N.A.
26.7
Protein Similarity:
51
N.A.
N.A.
51
N.A.
44.5
P-Site Identity:
0
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
13
0
0
44
0
0
7
13
13
7
7
7
0
0
% A
% Cys:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
7
0
7
0
0
0
7
13
0
7
0
% D
% Glu:
0
7
13
7
0
0
0
0
7
50
13
0
57
13
0
% E
% Phe:
0
7
0
0
13
7
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
19
% G
% His:
7
7
7
7
0
0
0
0
0
0
0
0
0
7
7
% H
% Ile:
0
7
0
0
7
0
13
13
0
0
0
13
13
0
13
% I
% Lys:
0
0
13
0
7
7
0
7
44
19
0
7
7
0
0
% K
% Leu:
0
50
7
13
0
0
13
7
7
0
44
0
0
44
0
% L
% Met:
7
0
0
0
7
0
44
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
7
7
13
7
7
0
7
44
% N
% Pro:
7
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
13
0
0
44
0
63
0
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
38
7
7
7
7
0
13
0
7
7
7
7
0
% R
% Ser:
7
0
0
0
13
7
0
50
0
0
7
0
0
0
7
% S
% Thr:
7
0
0
7
0
7
7
7
7
0
7
7
13
0
7
% T
% Val:
0
0
0
13
0
0
7
0
0
7
7
32
0
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _